Prior to the founding of the Institute of Science and Technology Austria (IST Austria), a different establishment existed in the compound. It was a neurological and psychiatric hospital of the province of Lower Austria, which operated here for approximately 120 years.

Between 1939 and 1945, unforgivable medical crimes were committed by the Nazi doctors in this hospital. Several thousand patients of all ages were murdered. Some within the hospital, either intentionally and directly or by cruelty and negligence; others were transferred to centers of extermination elsewhere. This memorial is dedicated to these victims.

The memorial is located in the park of IST Austria. It is open to the public at all times.